阶段1Mesothelioma

02. Stage 1 Symptoms

1期间皮瘤的症状是什么？万博专业版

早期间皮瘤症状经常被忽视万博专业版或被误诊为更常见的疾病。患者经常在患者进万博专业版行时经常发现1阶段间皮瘤成像扫描for another reason. However, patients may be able to recognize early-stage symptoms, especially with a known history of asbestos exposure.

阶段1Mesothelioma Symptoms*

• Abdominal pain
• Chest pain
• Coughing
• Shortness of breath
• 疲劳
• Fever

_{*清单是普通胸膜，腹膜，心心和睾丸症状的组合}

Patients should seek medical care as soon as they recognize potential mesothelioma symptoms. In most cases, early detection is the best way to improvemesothelioma life expectancy。

03. Stage 1 Types

阶段1Mesothelioma by Type

There are four maintypes of mesothelioma，包括胸膜，腹膜，心包和睾丸间皮瘤。万博专业版每种类型都起源于身体的不同区域，影响不同的器官和淋巴结。阶段1间皮瘤进展万博专业版将根据原始肿瘤的位置而有所不同。

阶段1Pleural Mesothelioma

Malignant pleural mesothelioma是最常见的类型的间皮瘤。万博专业版胸膜米esothelioma can be further classified as stage 1A or stage 1B using the TNM staging system.

对于第1A期胸膜间皮瘤和1B期胸膜间皮瘤，万博专业版癌症存在于胸部仅一侧的胸膜衬里中。此时，淋巴结或远处器官还没有转移。

The differentiating factor between stage 1A and stage 1B is the impact on nearby tissues. During stage 1B, the cancer may have spread into the lung tissue, diaphragm, chest wall, pericardium (thin tissue surrounding the heart), chest cavity fat or other nearby tissue linings.

阶段1Pleural Mesothelioma Characteristics

• 阶段1胸膜间皮瘤可以进一步分为1万博专业版A期和1B期。
• Mesothelioma tumors develop in the pleural lining on one side of the chest.
• There is no distant metastasis.

阶段1腹膜间皮瘤万博专业版

Peritoneal mesothelioma是第二常见类型。它没有自己的分期系统，但通常是使用腹膜癌指数（PCI）或TNM分期系统修改版本进行的。PCI分数腹部区域并使用得分总数来确定阶段。

阶段1peritoneal mesothelioma indicates the tumor is localized within the abdominal lining. The cancer has not yet spread to other organs or lymph nodes.

Early symptoms of mesotheliomaare typically mild and treatment options, such as surgery incombination with hyperthermic intraperitoneal chemotherapy(HIPEC), can be highly effective. HIPEC is a highly concentrated, heated chemotherapy that fills the abdominal cavity.

阶段1腹膜间皮瘤万博专业版Characteristics

• 阶段1peritoneal cancer has a PCI score of less than 11.
• Mesothelioma tumors are localized within the lining of the abdomen.
• There is no distant metastasis.

阶段1Pericardial Mesothelioma

仅占所有间皮瘤诊断的1-2％，万博专业版pericardial mesotheliomadoes not have a definitive staging system. This type progresses quickly and is not normally recognized in the early stages. A stage 1 diagnosis would imply the cancer is localized within the pericardium (heart lining) and has not yet spread to other areas of the body.

阶段1Testicular Mesothelioma

Testicular mesotheliomais also rare, accounting for only 1% of all mesothelioma cases. It does not have a definitive staging system. A stage 1 diagnosis would imply the cancer is localized to the tunica vaginalis (testicle linings) with no distantmetastasis或淋巴结受累。

04. Stage 1 Prognosis

阶段1Mesothelioma Prognosis

预后for stage 1 mesothelioma predicts how long the patient will live, as well as how the disease will progress. Theprognosis对于第1阶段，是间皮瘤阶段中最有利的。万博专业版

早期检测允许患者早期开始治疗。治疗通常更具侵略性，并且针对第1阶段和第2阶段，因为癌症位于一个区域。

To support early detection, patients should be aware of all potential mesothelioma symptoms. Patients with a known history of asbestos exposure should disclose their exposure to their physician and maintain regular checkups.

有几个因素可以影响病人prognosis, including tumor location, cell type, patient age and overall health.

Factors Influencing Stage 1 Mesothelioma Prognosis

• Tumor location:阶段1peritoneal and stage 1 pleural mesothelioma typically have the best prognosis.
• Cell type:阶段1epithelial mesotheliomatypically has a better prognosis than stage 1sarcomatoid mesothelioma。
• 患者年龄：Younger stage 1 mesothelioma patients typically have a better prognosis than older patients.
• Overall health:与健康状况不佳或其他现有医疗状况相比，健康状况更好的患者通常具有更好的预后。

阶段1Mesothelioma Life Expectancy and Survival Rate

Life expectancyis an estimate of how long the patient is expected to live. Mesothelioma studies rarely capture stage 1 life expectancy, as patients often survive past the end of the studies.

As a result, survival statistics are typically represented as median survival and survival rates. The median survival for stage 1 mesothelioma is 21 months (compared to 19 months for stage 2 pleural mesothelioma).

Survival rates show what percentage of individuals with a particular diagnosis have survived for a certain number of years.Mesothelioma survival rates通常以2年和5年的增量显示。平均而言，1阶段间皮瘤患者的存活率高于晚万博专业版期间皮瘤的患者。

• 1期胸膜间皮瘤的2年生存率为41％。万博专业版
• The 5-year survival rate for stage 1 pleural is 33%.

有几个因素会影响生存。患者和亲人应咨询间皮瘤专家，以准确了解其特定情况的预期寿命。万博专业版患者可能能够及时，积极地增加预期寿命万博专业版间皮瘤治疗。

05. Can It Be Cured?

Can Stage 1 Mesothelioma Be Cured?

Currently, there is no cure for mesothelioma cancer. However, mesothelioma researchers continue to develop improved diagnostic tools and treatment options. In many cases, treatment can extend patient life expectancies.Multimodal therapy表现出了特别的成功。

Some stage 1 or stage 2mesothelioma survivorsare now cancer-free. Their stories offer hope and inspiration to those newly diagnosed with the disease.

06. Stage 1 Treatment

阶段1间皮瘤治疗万博专业版

Patients with stage 1 mesothelioma usually have more treatment options available to them than those diagnosed at later stages. Treatments can also be more aggressive. At this stage, the cancer is localized and can be better targeted with treatment. Stage 1 patients are generally in good health, allowing them to better withstand treatment side effects.

阶段1万博专业版间皮瘤治疗plans typically involvemultimodal therapy。Multimodal therapy involves a combination of treatments. Multimodal treatment plans often include surgery, chemotherapy or radiation therapy, but may also involve experimental options. Not all patients can pursue these options.Mesothelioma doctors可以为患者的个体病例提供最佳的见解。

阶段1间皮瘤治疗万博专业版Options

• Surgery
• Chemotherapy
• Radiation therapy
• Immunotherapy
• 临床试验

Surgery

手术旨在消除尽可能多的癌症。第1阶段间皮瘤是万博专业版局部的，因此患者可以接受完整的手术切除。完整的切除旨在去除任何可见的间皮瘤肿瘤和受影响的组织。万博专业版手术后通常进行化学疗法以杀死其余的癌细胞。

普通阶段1间皮瘤手术包括胸膜切万博专业版除术，pleurectomy/decortication和胸膜外肺切除术（epp）。

• A pleurectomy removes the lining in the lung (pleural lining).
• 胸膜切除术/剥外皮消除了胸膜ning and nearby diseased tissue.
• An extrapleural pneumonectomy removes a patient’s lung, a portion of the diaphragm, the lining of the lungs and the lining of the heart.

Chemotherapy

Chemotherapy treats mesothelioma by killing cancer cells, shrinking tumors and preventing growth. Chemotherapy for stage 1 mesothelioma patients is often used after surgery to kill any remaining cancer cells and help prevent recurrence.

放射治疗

Radiation treats mesothelioma by damaging cancer cells, which causes cell death or slows growth. The human body then naturally processes and removes dead cancer cells. Radiation is a targeted treatment that can cause harm to vital organs, such as the lungs. As a result, radiation is most effective when used to treat a stage 1 tumor that is localized.

Immunotherapy

与传统疗法相比，免疫疗法是间皮瘤的一种新疗法，例如手术，化学疗法和放射治疗。万博专业版免疫疗法刺激患者的免疫系统与癌细胞抗衡。一些免疫疗法药物，例如Keytruda®, have been successful in extending patient life expectancies.

Clinical Trials

阶段1mesothelioma patients may be able to participate in clinical trials. Clinical trials utilize experimental treatments not yet available to all patients. This option is particularly helpful for patients who do not respond to standard treatment options.

Patients should discuss treatment options with their medical care team. In addition to standard treatment options, there are alsoalternative treatments这可能证明有助于减少治疗副作用和疾病症状。