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石棉会引起几种形式的癌症。最著名的石棉癌是间皮瘤和肺癌。万博专业版但是,石棉暴露也会引起卵巢和喉部(语音盒)癌症。石棉还可能增加其他癌症,例如乳腺癌,胃癌和结肠癌的风险。


01.概述

石棉相关癌症的概述

Asbestos is a naturally occurring mineral that causes several medical conditions. These asbestos-related illnesses include several lung diseases andtypes of cancer。Researchers have conclusively linked the following cancers toasbestos exposure

一些证据还表明,石棉暴露可能有助于胃,咽和结直肠癌的发作。咽癌是咽癌(喉咙的最高部分)。随着研究的继续,医生可能会更好地理解石棉如何导致多种形式的癌症。

How Does Asbestos Cause Cancer?

Asbestos fibers足够小,可以呼吸或摄入。一旦进入体内,免疫系统几乎不可能清除它们。因此,石棉纤维可能保留在体内多年,从而造成不必要的健康影响。随着时间的流逝,这些纤维会引起炎症和疤痕。最终,这些过程可能导致癌症的发展和其他状况石棉病

Asbestos cancers can occur in different areas of the body, affecting various types of tissue. As such, each form of asbestos cancer comes with its own unique prognosis and treatment options.

02. Voice Box Cancer

Laryngeal Cancer

喉癌发生在语音盒中或声带周围的组织。喉癌的危险因素包括:

  • Asbestos exposure
  • 过度饮酒
  • Smoking

这种形式的癌症可能会引起诸如喉咙痛,持续性咳嗽或耳朵疼痛之类的症状。医生可以使用许多测试来诊断喉癌。这些测试可能包括体格检查,成像测试以及活检程序和分析。

Approximately 12,600 new cases of pharyngeal cancer occur each year in the United States. It is unclear how many of those cases may be related to asbestos exposure.

Survival Information

喉癌survival depends on several factors, including cancer stage and overall patient health. Depending on the exact location of cancer within the larynx, 5-year survival rates range from 23% to 83%.

Asbestos Link

Multiple studies have investigated the relationship between asbestos and laryngeal cancer. Several of these studies looked at groups of people withoccupational asbestos exposure

In these groups, researchers found asbestos increased the risk of dying from laryngeal cancer by 43% to more than 167%. This means some studies found asbestos exposure more than doubled a person’s risk of dying from laryngeal cancer.

03.肺癌

肺癌

肺癌在肺组织内发展。它有两种主要形式:小细胞和非小细胞肺癌(SCLC和NSCLC)。肺癌的危险因素包括:

  • Asbestos exposure
  • Chronic inflammation
  • Exposure to carcinogens including asbestos and radon
  • Smoking

Patients withasbestos-related lung cancer可能出现的症状,比如咳嗽、疲劳和shortness of breath. Doctors use a combination of physical examination, imaging, blood and biopsy tests to diagnose lung cancer.

Experts estimate there are around 2,000 – 3,200 lung cancer deaths each year in the United States. A small percentage of these cases may be asbestos-related lung cancers.

Survival Information

Lung cancer prognosis depends on stage at diagnosis, treatment choices and patient factors. Reported 5-year survival rates range from 3% to 63% according to the National Cancer Institute.

Asbestos Link

石棉暴露与肺癌之间的联系已通过医学研究很好地建立。一项研究包括暴露于石棉的工人。在这项研究中,这些工人死于肺癌的风险高96%。

Another study found a relationship between the amount and duration of asbestos exposure and lung cancer risk. This means the risk of dying of lung cancer increased as the intensity of asbestos exposure increased.

04. Ovarian Cancer

Ovarian Cancer

卵巢癌develops in the ovaries. It may arise in any of three main cell types: epithelial cells, germ cells and stromal cells. Risk factors for ovarian cancer include:

  • Asbestos exposure
  • Having children after age 35
  • 拥有卵巢癌或其他癌症的家族史
  • 有乳腺癌病史
  • Increasing age
  • 从来没有足月怀孕
  • Obesity
  • Smoking
  • Undergoing fertility treatment
  • 更年期后使用激素疗法

卵巢癌patients commonly experience bloating, abdominal pain, a feeling of fullness and urinary urgency. Doctors use an array of common medical tests to diagnose ovarian cancer. These tests may include a physical exam, imaging tests or biopsies.

Experts estimate approximately 21,400 American women will receive an ovarian cancer diagnosis in 2021.

Survival Information

卵巢癌prognosis depends on a number of factors. In general, earlier diagnosis leads to better outcomes. Depending on cancer stage, 5-year survival rates for ovarian cancer range from 31% to 98%.

Asbestos Link

There are relatively few studies investigating the link between asbestos and ovarian cancer. This stems from the fact that men make up the majority of individuals exposed to asbestos at work. However, a couple of large studies have looked at women with a history of occupational asbestos exposure.

一项研究调查了1,327名帮助制造含石棉面罩的妇女。他们死于卵巢癌的风险比普通人群高48%至175%。

The International Agency for Research on Cancer (IARC) recently released a report on asbestos and cancer. After weighing the available evidence, the IARC group concluded asbestos causes ovarian cancer.

滑石粉,石棉和卵巢癌

过去,许多妇女使用滑石粉每天,通常在生殖区域。滑石粉来自滑石,这是一种由镁,硅和氧气组成的矿物质。但是,滑石沉积物​​通常自然含有石棉。

In fact, Johnson & Johnson’s baby powder recentlytested positive for asbestos fibers。约翰逊和约翰逊(Johnson&Johnson)在2020年停止了基于北美滑石粉的产品。尽管如此,许多妇女可能通过受污染的滑石粉暴露于石棉。

At least 35,000 women have filed lawsuits blaming talcum powder for their ovarian cancer diagnoses. Some studies have found a weak association between talc and ovarian cancer. Additionally, the International Agency for Research on Cancer (IARC) classifies asbestos-containing talc as “carcinogenic to humans.”

2018年,圣路易斯的陪审团向起诉约翰逊和约翰逊的妇女授予了近47亿美元。原告声称该公司的基于滑石粉的产品使他们发展了卵巢癌。

约翰逊和约翰逊对判决提出上诉,该裁决在2020年降至21亿美元。但是,最高法院拒绝了该公司随后的上诉。

05.其他癌症

其他可能与石棉相关的癌症

Many researchers have studied the potential link between asbestos and various cancers. For some cancers, these studies have been contradictory. Some have found a strong connection between asbestos and certain cancers. Others have found no evidence of the same connection.

需要进行其他研究来确定石棉与下面的癌症之间的真实关系。但是,至少有一些证据表明石棉与以下每种癌症之间的联系。

乳腺癌

乳腺癌发生在乳腺组织中。大多数病例发生在女性中,但男性也可以患乳腺癌。在乳腺癌中发现肿块或肿块是乳腺癌的最常见症状。

研究尚未在石棉和乳腺癌之间建立明确的联系。但是,一项研究确实找到了潜在的联系。研究人员调查了近900,000名芬兰妇女的癌症报告。其中一些妇女从事将她们暴露于石棉的工作。

石棉暴露与乳腺癌风险增加10%至70%有关。

Asbestos and Breast Cancer Quick Facts

  • Yearly Cases:300,000*
  • Common Symptoms:乳房中的肿块或肿块
  • 5-Year Survival Rate:~90%
  • Asbestos Link:May increase breast cancer risk by 10% to 80%

*这是所有乳腺癌病例的估计值,不一定是与石棉相关的乳腺癌。

Colon Cancer and Colorectal Cancers

Colorectal cancer occurs in the colon and rectum. The colon is the portion of the large intestine under the stomach. The rectum is the portion of the large intestine that connects the colon to the anus. Colorectal cancers may be called colon or rectal cancer depending on where they start.

A recent study investigated the link between asbestos and colorectal cancer in 14,515 men. It found asbestos exposure associated with a 14% higher than normal risk of colorectal cancers.

Asbestos and Colorectal Cancer Quick Facts

  • Yearly Cases:150,000*
  • Common Symptoms:Sustained bowel habit changes and rectal bleeding or bloody stool
  • 5-Year Survival Rate:〜65%
  • Asbestos Link:May increase colorectal cancer risk by 14%

*This is an estimate of all colorectal cancer cases, not necessarily asbestos-linked colorectal cancer.

食道癌

食道癌是一种在食道内膜中发展的癌症。它有两种主要形式:鳞状细胞癌和腺癌。

At least 25 studies have examined the relationship between asbestos exposure and esophageal cancer. One such study looked at cancer rates in nearly 7,000 Australian asbestos miners. The asbestos miners had a 20% higher risk of dying from esophageal cancer than the general public.

Another study looked at cancers in 3,072 asbestos-exposed workers from South Carolina. These workers were 87% more likely to die of esophageal cancer than the average person.

Asbestos and Esophageal Cancer Quick Facts

  • Yearly Cases:19,000*
  • Common Symptoms:吞咽困难,胸痛和体重减轻
  • 5-Year Survival Rate:〜20%
  • Asbestos Link:May increase risk for dying of esophageal cancer by 20% to 87%

*这是对所有食管癌病例的估计值,不一定是与石棉相关的食管癌。

肾癌

Kidney cancer is a cancer that occurs in one or both kidneys. Early kidney cancers might not cause symptoms. When symptoms do arise, they may include bloody urine, back pain on one side and a lump on the side or lower back.

一些研究未能发现石棉和肾癌之间的关联。但是,最近对近3200名石棉暴露男性的研究确实找到了关系。在这项研究中,任何数量的石棉暴露都与肾癌风险增加20%有关。石棉暴露水平的增加与肾癌的风险更高有关。

石棉和肾癌快速事实

  • Yearly Cases:76,000*
  • Common Symptoms:Bloody urine, one-sided back pain and a lump on the side or lower back
  • 5-Year Survival Rate:〜76%
  • Asbestos Link:May increase kidney cancer risk by 14%

*This is an estimate of all kidney and renal cancer cases, not necessarily asbestos-linked kidney and renal cancer.

Pharyngeal Cancer

Pharyngeal or oropharyngeal cancer is a cancer of the part of the throat just behind the mouth (the pharynx). Almost all pharyngeal cancers are squamous cell carcinomas.

A relatively small number of studies have investigated the relationship between asbestos and cancer of the pharynx. One study of 58,279 asbestos-exposed men included 53 cases of pharyngeal cancer. The asbestos-exposed men had more than twice the risk of developing pharyngeal cancer as those without asbestos exposure.

但是,作者指出他们的研究相对较小。为了更好地了解石棉和咽癌之间的关系,需要进一步的研究。

Asbestos and Pharyngeal Cancer Quick Facts

  • Yearly Cases:54,000*
  • Common Symptoms:Mouth pain, sore throat and difficulty swallowing
  • 5-Year Survival Rate:〜67%
  • Asbestos Link:May double pharyngeal cancer risk

*This is an estimate of all oral and pharyngeal cancer cases, not necessarily asbestos-linked oral and pharyngeal cancer.

前列腺癌

前列腺癌是前列腺中细胞的癌症。大多数前列腺癌是通过早期筛查发现的。

专家估计,将在2021年诊断出约25万例前列腺癌病例。目前尚不清楚其中有多少病例可能与石棉有关。但是,一些研究人员提出了石棉和前列腺癌之间的联系。

A recent study analyzed nearly 16,000 cases of prostate cancer. These cases occurred among a study group of more than 700,000 people. Asbestos exposure increased the risk of prostate cancer by approximately 10%. However, cases of environmental or occupational asbestos exposure carried a 25% increased risk of prostate cancer.

researchers concluded asbestos exposure seems to increase the risk of prostate cancer.

Asbestos and Prostate Cancer Quick Facts

  • Yearly Cases:250,000*
  • Common Symptoms:Urination problems, bloody urine, erectile dysfunction and back or hip pain
  • 5-Year Survival Rate:〜98%
  • Asbestos Link:May increase prostate cancer risk by approximately 10% to 25%

*这是对所有前列腺癌病例的估计值,不一定是与asbestos相关的前列腺癌。

Stomach Cancer

Stomach or gastric cancer is a cancer of the cells in the stomach. Experts estimate approximately 27,000 new cases of stomach cancer will occur in the United States in 2021. Some of them may be asbestos-related, but the evidence is still inconclusive.

A few studies have found a link between asbestos exposure and stomach cancer. Recently, investigators analyzed cancer cases across 32 different medical studies. They found asbestos exposure increased the risk of dying from stomach cancer by 19%.

Another study looked at the incidence of stomach cancer in people exposed to asbestos-contaminated talcum powder. Among more than 580,000 people, the researchers found nearly 22,000 talc users.

滑石粉暴露的个体的风险是患胃癌与非暴露个体的两倍以上。研究人员得出结论,(被石棉污染)滑石粉与胃癌之间可能存在联系。

石棉和胃癌快速事实

  • Yearly Cases:27,000*
  • Common Symptoms:Appetite loss, weight loss and stomach pain
  • 5-Year Survival Rate:〜32%
  • Asbestos Link:可能会使胃风险增加更多19%或更多

*这是所有胃癌病例的估计,不一定是与石棉连接的胃癌。

06. What to Do

What to Do if You Were Exposed to Asbestos

Numerous cancers have been linked to asbestos exposure. Individuals with a history of asbestos exposure may want to speak with a physician. Doctors can help advise patients on the best ways to monitor for potential石棉相关癌症的症状并建议可能的筛选。

这可能有助于确定早期阶段的任何潜在石棉癌。通常,较早的癌症检测允许更多治疗选择和更好的生存期。

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