01. Ongoing Clinical Trials
Ongoing Mesothelioma Clinical Trials
Clinical trialsare designed to testnew treatments尽可能的高效。这个设计我的一部分ans only a certain number of patients can be accepted into each study. Once a mesothelioma study reaches this enrollment target, no additionalmesothelioma patientsare accepted. The study is still considered to be ongoing, as doctors continue treating and monitoring existing study patients.
Some clinical trials release preliminary study results during this time period. For instance, theCheckMate 743 clinical trialdid this in 2020. CheckMate 743 investigated the use of two immunotherapy drugs compared to standard chemotherapy treatment.
The immunotherapy drug combination (nivolumab and ipilimumab) performed better than standard chemotherapy. Patients treated with the immunotherapy drugs lived about four months longer than those receiving chemotherapy.
After reviewing the study results, theU.S. Food and Drug Administration (FDA) approved the immunotherapy drugs. Specifically, nivolumab and ipilimumab were approved for the treatment of inoperablepleural mesothelioma.
If you or a loved one are considering enrolling in a clinical trial, you can find open studies on ourClinical Trials – Recruitingpage.
02. List of Ongoing Clinical Trials
Ongoing Mesothelioma Clinical Trials Not Recruiting Patients
Provided below is a list of mesothelioma trials that are no longer accepting new patients.
Note:The information below is provided by ClinicalTrials.gov.
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:November 30, 2021
Status:Active, not recruiting
Locations:Tampa, FL.
A Clinical Study of Anetumab Ravtansine in Adults With Solid Tumors Who Have Been Treated in Previous Bayer-sponsored Anetumab Ravtansine Studies
Conditions:
拉斯维加斯t Updated:November 11, 2021
Status:Active, not recruiting
Locations:Chicago, IL. Bethesda, MD. Nashville, TN. Dallas, TX.
First-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express Mesothelin
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:November 11, 2021
Status:Active, not recruiting
Locations:Bethesda, MD. Houston, TX.
Phase II MEDI4736 in Combination With Chemotherapy for First-Line Treatment of Unresectable Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:November 10, 2021
Status:Active, not recruiting
Locations:拉霍亚,CA。洛杉矶CA。斯坦福,CA,傲罗a, CO. Miami, FL. Atlanta, GA. Chicago, IL. Evanston, IL. Baltimore, MD. Ann Arbor, MI. Saint Louis Park, MN. Saint Louis, MO. New Brunswick, NJ. New York, NY. Philadelphia, PA. Pittsburgh, PA. Dallas, TX. Fairfax, VA. Seattle, WA. Wauwatosa, WI.
CheckpOiNt Blockade For Inhibition of Relapsed Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:November 6, 2021
Status:Active, not recruiting
Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin
Conditions:Mesothelioma, Pleural Diseases
拉斯维加斯t Updated:2021年10月29日
Status:Active, not recruiting
Locations:Basking Ridge, NJ. Middletown, NJ. Montvale, NJ. Commack, NY. Harrison, NY. New York, NY.
Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:October 25, 2021
Status:Active, not recruiting
Locations:Los Angeles, CA. San Francisco, CA. Tampa, FL. Kansas City, KS. Baltimore, MD. Baltimore, MD. Minneapolis, MN. Rochester, MN. New York, NY. Philadelphia, PA. Dallas, TX.
Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant, Lung Neoplasms
拉斯维加斯t Updated:October 20, 2021
Status:Active, not recruiting
Locations:Scottsdale, AZ. La Jolla, CA. Los Angeles, CA. San Francisco, CA. Santa Monica, CA. New Haven, CT. Newark, DE. Tampa, FL. Augusta, GA. Chicago, IL. Peoria, IL. Baltimore, MD. Baltimore, MD. Minneapolis, MN. New York, NY. Rochester, NY. Durham, NC. Canton, OH. Philadelphia, PA. Dallas, TX. Houston, TX.
Phase I Trial HIPEC With Nal-irinotecan
Conditions:Mesothelioma, Adenocarcinoma, Mucinous, Cystadenocarcinoma, Pseudomyxoma Peritonei
拉斯维加斯t Updated:October 19, 2021
Status:Active, not recruiting
Locations:Lexington, KY. Stony Brook, NY.
Pembrolizumab in Treating Patients With Malignant Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant, Lung Neoplasms
拉斯维加斯t Updated:October 8, 2021
Status:Active, not recruiting
Locations:Chicago, IL.
Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant, Lung Neoplasms
拉斯维加斯t Updated:October 2, 2021
Status:Active, not recruiting
Locations:Phoenix, AZ. Scottsdale, AZ. Hot Springs, AR. Arroyo Grande, CA. Duarte, CA. Sacramento, CA. Colorado Springs, CO. Colorado Springs, CO. Denver, CO. Durango, CO. Durango, CO. Golden, CO. Lakewood, CO. Lakewood, CO. Littleton, CO. Longmont, CO. Longmont, CO. Parker, CO. Parker, CO. Pueblo, CO. Pueblo, CO. Thornton, CO. Jacksonville, FL. Boise, ID. Caldwell, ID. Coeur d'Alene, ID. Meridian, ID. Nampa, ID. Post Falls, ID. Sandpoint, ID. Aurora, IL. Bloomington, IL. Canton, IL. Carbondale, IL. Carterville, IL. Carthage, IL. Centralia, IL. Danville, IL. Decatur, IL. Decatur, IL. Effingham, IL. Effingham, IL. Eureka, IL. Galesburg, IL. Galesburg, IL. Kewanee, IL. Macomb, IL. Mattoon, IL. O'Fallon, IL. Ottawa, IL. Pekin, IL. Pekin, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peoria, IL. Peru, IL. Peru, IL. Princeton, IL. Springfield, IL. Springfield, IL. Springfield, IL. Swansea, IL. Urbana, IL. Urbana, IL. Yorkville, IL. Ames, IA. Ames, IA. Boone, IA. Clive, IA. Clive, IA. Council Bluffs, IA. Creston, IA. Des Moines, IA. Des Moines, IA. Fort Dodge, IA. Jefferson, IA. Marshalltown, IA. West Des Moines, IA. Lawrence, KS. Wichita, KS. Wichita, KS. Wichita, KS. Bardstown, KY. Corbin, KY. Lexington, KY. Lexington, KY. London, KY. Louisville, KY. Louisville, KY. Louisville, KY. Shepherdsville, KY. New Orleans, LA. Brownstown, MI. Clinton Township, MI. Detroit, MI. Jackson, MI. Shelby, MI. West Bloomfield, MI. Rochester, MN. Bonne Terre, MO. Cape Girardeau, MO. Cape Girardeau, MO. Jefferson City, MO. Saint Louis, MO. Sainte Genevieve, MO. Sullivan, MO. Sunset Hills, MO. Anaconda, MT. Billings, MT. Bozeman, MT. Great Falls, MT. Great Falls, MT. Helena, MT. Kalispell, MT. Missoula, MT. Grand Island, NE. Kearney, NE. Kearney, NE. Lincoln, NE. Omaha, NE. Omaha, NE. Omaha, NE. Omaha, NE. Omaha, NE. Papillion, NE. Henderson, NV. Henderson, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Las Vegas, NV. Reno, NV. Reno, NV. Reno, NV. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Cincinnati, OH. Lawton, OK. Oklahoma City, OK. Pittsburgh, PA. Charleston, SC. Chattanooga, TN. Hixson, TN. Ooltewah, TN. Bryan, TX. Conroe, TX. Dallas, TX. Houston, TX. Houston, TX. Houston, TX. League City, TX. Richardson, TX. Sugar Land, TX. Charlottesville, VA. Bellevue, WA. Bremerton, WA. Bremerton, WA. Burien, WA. Enumclaw, WA. Federal Way, WA. Lakewood, WA. Poulsbo, WA. Renton, WA. Seattle, WA. Seattle, WA. Seattle, WA. Tacoma, WA. Tacoma, WA. Cody, WY. Sheridan, WY.
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Conditions:Empyema, Empyema, Pleural, Mesothelioma, Pleural Effusion, Malignant, Pleural Neoplasms, Pleural Effusion, Pulmonary Atelectasis, Pneumothorax, Pleural Diseases, Hemothorax, Pericardial Effusion, Lymphadenopathy
拉斯维加斯t Updated:September 30, 2021
Status:Active, not recruiting
Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors
Conditions:Carcinoma, Renal Cell, Mesothelioma
拉斯维加斯t Updated:September 29, 2021
Status:Active, not recruiting
Locations:Mobile, AL. Scottsdale, AZ. Tucson, AZ. Baltimore, MD. Boston, MA. Boston, MA. Detroit, MI. Nashville, TN. Nashville, TN. Houston, TX. Houston, TX. San Antonio, TX.
Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors
Conditions:Adenocarcinoma, Mesothelioma, Cholangiocarcinoma
拉斯维加斯t Updated:September 29, 2021
Status:Active, not recruiting
Locations:Bethesda, MD.
MEDI4736 Or MEDI4736 + Tremelimumab In Surgically Resectable Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:September 24, 2021
Status:Active, not recruiting
Locations:Houston, TX.
Intrapleural Cryotherapy for Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:September 14, 2021
Status:Active, not recruiting
Locations:Rochester, MN.
A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549
Conditions:Carcinoma, Non-Small-Cell Lung, Melanoma, Triple Negative Breast Neoplasms, Mesothelioma, Mesothelioma, Malignant, Neoplasms, Squamous Cell, Carcinoma, Squamous Cell, Head and Neck Neoplasms, Adrenocortical Carcinoma
拉斯维加斯t Updated:September 13, 2021
Status:Active, not recruiting
Locations:San Diego, CA. Santa Monica, CA. Port Saint Lucie, FL. Atlanta, GA. Boston, MA. Boston, MA. Boston, MA. Hackensack, NJ. New York, NY. Houston, TX. San Antonio, TX.
Pevonedistat Alone and in Combination With Chemotherapy in Patients With Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:September 10, 2021
Status:Active, not recruiting
Locations:Basking Ridge, NJ. Middletown, NJ. Montvale, NJ. Commack, NY. Harrison, NY. New York, NY. Rockville Centre, NY. Uniondale, NY.
A Study of Pembrolizumab in Combination With Cisplatin and Pemetrexed in Advanced Malignant Pleural Mesothelioma (MPM) (MK-3475-A17)
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:September 8, 2021
Status:Active, not recruiting
Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin
Conditions:Neoplasms, Mesothelioma, Mesothelioma, Malignant, Lung Neoplasms
拉斯维加斯t Updated:September 7, 2021
Status:Active, not recruiting
Locations:Duarte, CA. Los Angeles, CA. Los Angeles, CA. Pasadena, CA. Sacramento, CA. Aurora, CO. Baltimore, MD. Ann Arbor, MI. Rochester, MN. Columbus, OH. Pittsburgh, PA. Nashville, TN. Nashville, TN. Madison, WI.
A Study of Rebastinib (DCC-2036) in Combination With Carboplatin in Patients With Advanced or Metastatic Solid Tumors
Conditions:Neoplasms
拉斯维加斯t Updated:August 10, 2021
Status:Active, not recruiting
Locations:San Francisco, CA. Santa Monica, CA. Chicago, IL. Kansas City, KS. Charlotte, NC. Columbus, OH. Nashville, TN. Houston, TX. San Antonio, TX.
A Study of LY3023414 in Participants With Advanced Cancer
Conditions:Neoplasms, Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:August 5, 2021
Status:Active, not recruiting
Locations:Los Angeles, CA. New York, NY. Oklahoma City, OK. Philadelphia, PA. Nashville, TN. Nashville, TN.
一项研究的安全性、耐受性和Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
Conditions:Neoplasms
拉斯维加斯t Updated:July 29, 2021
Status:Active, not recruiting
Locations:La Jolla, CA. Sacramento, CA. Stanford, CA. New Haven, CT. Huntersville, NC. Greenville, SC. Dallas, TX. San Antonio, TX. Charlottesville, VA. Fairfax, VA.
Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:July 28, 2021
Status:Active, not recruiting
Locations:Alessandria, Alabama. Catania, Connecticut.
Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:June 15, 2021
Status:Active, not recruiting
Locations:Houston, TX.
Stereotactic Body Radiation Therapy and Avelumab Immunotherapy for Treatment of Malignant Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant, Lung Neoplasms
拉斯维加斯t Updated:June 11, 2021
Status:Active, not recruiting
Locations:Basking Ridge, NJ. Middletown, NJ. Commack, NY. Harrison, NY. New York, NY. Rockville Centre, NY. Uniondale, NY.
Tazemetostat Rollover Study (TRuST): An Open-Label, Rollover Study
Conditions:Lymphoma, Sarcoma, Lymphoma, Non-Hodgkin, Lymphoma, Large B-Cell, Diffuse, Mesothelioma, Sarcoma, Synovial, Carcinoma, Medullary
拉斯维加斯t Updated:May 26, 2021
Status:Active, not recruiting
Locations:Tucson, AZ. Tampa, FL. Ann Arbor, MI. New York, NY. New York, NY.
Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies
Conditions:Neoplasms
拉斯维加斯t Updated:May 21, 2021
Status:Active, not recruiting
Locations:Los Angeles, CA. Gainesville, FL. Detroit, MI. Saint Louis, MO. Hackensack, NJ. New York, NY. Chapel Hill, NC. Oklahoma City, OK. Portland, OR. Philadelphia, PA. Pittsburgh, PA. Nashville, TN. Dallas, TX. Houston, TX. Seattle, WA.
Psychosocial Needs and Exploration of Online Support for Patients With Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:May 10, 2021
Status:Active, not recruiting
Locations:New York, NY.
A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
Conditions:Neoplasms
拉斯维加斯t Updated:May 3, 2021
Status:Active, not recruiting
Locations:La Jolla, CA. Chicago, IL. Huntersville, NC. San Antonio, TX. Fairfax, VA.
TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patients
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:April 11, 2021
Status:Active, not recruiting
Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:March 24, 2021
Status:Active, not recruiting
Locations:San Francisco, CA. New Haven, CT. Tampa, FL. Chicago, IL. Baltimore, MD. Detroit, MI. Grand Rapids, MI. Rochester, MN. New York, NY. Cleveland, OH. Jefferson Hills, PA. Philadelphia, PA. Houston, TX. Morgantown, WV.
Screening of Alberta Asbestos Exposed Workers for Lung Cancer and Mesothelioma
Conditions:Lung Neoplasms, Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:March 4, 2021
Status:Active, not recruiting
Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors
Conditions:Carcinoma, Merkel Cell, Carcinoma, Carcinoma, Squamous Cell, Mesothelioma, Mesothelioma, Malignant, Neuroendocrine Tumors, Nasopharyngeal Carcinoma, Lung Neoplasms, Carcinoma, Neuroendocrine
拉斯维加斯t Updated:February 23, 2021
Status:Active, not recruiting
Locations:Houston, TX.
PembROlizuMab Immunotherapy Versus Standard Chemotherapy for Advanced prE-treated Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:February 8, 2021
Status:Active, not recruiting
Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma
Conditions:Vaccinia, Mesothelioma, Pleural Effusion, Malignant, Pleural Effusion
拉斯维加斯t Updated:January 19, 2021
Status:Active, not recruiting
Locations:New York, NY.
A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:October 6, 2020
Status:Active, not recruiting
A Double Blind, Placebo Controlled, Randomized Phase II Study Evaluating Gemcitabine With or Without Ramucirumab , for II Line Treatment MPM
Conditions:Mesothelioma, Mesothelioma, Malignant
拉斯维加斯t Updated:July 29, 2020
Status:Active, not recruiting